Primary leptomeningeal melanoma. Diagnosis by ultrastructural cytology of cerebrospinal fluid and cranial computed tomography

Cranial computed tomography of malignant melanoma.

Two hundred seventy-five cranial computed tomography (CT) scans performed on 179 patients with malignant melanoma were reviewed. Of the 101 patients with confirmed cerebral metastases, CT demonstrated lesions in 93. In 72% of these, areas of increased attenuation were present in the precontrast scan. These lesions also enhanced after contrast infusion. There was a direct correlation between the...

Cytology of cerebrospinal fluid: technical and diagnosis considerations.

The usefulness of cerebrospinal fluid cytology in the diagnosis of malignancy has been enhanced in recent years by the development of new techniques for increasing cellular yield. Micropore filters and a specially adapted cytocentrifuge have been used for this purpose with a resulting increase in cell concentration and in diagnostic accuracy. Cerbrospinal fluid examination has been found to be ...

Cerebrospinal fluid cytology

Changes on computed cranial tomography with aging: intracranial fluid volume.

A semiautomated computer analysis was developed to estimate fluid volumes in each hemicranium from computed tomography scans. The method was used to estimate total ventricular and sulcal fluid in 123 normal subjects aged 23-88 years. A wide range of normal values was found. The trend was for the estimated ventricular and sulcal fluid volumes to remain relatively constant until age 60 and then t...

Cranial computed tomography in the diagnosis of multiple sclerosis.

A group of 202 patients with suspected, probable or definite multiple sclerosis was studied, using cranial computed tomography (CT). Atrophy alone, or in combination with white-matter and periventricular lucencies, and areas of contrast enhancement, were the main abnormal findings in 52% of patients. Atrophy was detected in 44% of patients, and its frequency and severity correlated with disease...